This is applicable for client side scripting (both Catalog and table level)

Make them readonly, mandatory or clear all variable/field values when the respective field changes.

 var fieldArr = ['Field_A', 'Field_B', 'Field_C', 'Field_D', 'Field_E', 'Field_F'];

//add comma separated field names which you want to clear here


        for (var i = 0; i < fieldArr.length; i++) {
            g_form.clearValue(fieldArr[i]);
        }


//Similarly we can use other methods like - g_form.setReadOnly, g_form.setMandatory or g_form.setDisplay


    for (var i = 0; i < fieldArr.length; i++) {

        g_form.setReadOnly(fieldArr[i], true);

        if (g_form.getValue(fieldArr[i]) == "") {
            g_form.setDisplay(fieldArr[i], false);

        }
    }

Thanks to @Mike Patel